Raw Material: Somatropin (Humatrope 72 iu)
Manufacturer: LILLY TR
Package: 72 IU (24MG)
Available In Stock
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Do not use Humatrope
- if you are allergic (hypersensitive) to somatropin or any of the other ingredients of Humatrope
(e.g. metacresol, glycerol in the solvent) see section 6.
- and tell your doctor if you have an active tumour (cancer). Tumours must be inactive and you must have finished your anti-tumour treatment before you start your treatment with Humatrope.
- if you have already stopped growing and want to promote further growth in height (closed growth plates at the end of long bones). Your doctor will examine you to decide if you still require Humatrope after your bones have stopped growing.
- if you are very ill and require intensive medical care for a serious heart or abdominal operation, being treated for multiple injuries from an accident, or require mechanical breathing treatment following acute lung failure.
Warnings and Precautions
Talk to your doctor or pharmacist before using Humatrope.
If you have a replacement therapy with glucocorticoids, you should consult your doctor regularly, as you may need adjustment of your glucocorticoid dose.
If you have been treated for growth hormone deficiency during childhood, your doctor will re-examine you for growth hormone deficiency to decide if you require further Humatrope treatment during adulthood.
If you have completed previous anti-tumour therapy, a scan of your brain may be required before the start of Humatrope treatment. You should be examined regularly to make sure that the tumour does not come back or start growing.
A higher risk for having a second tumour (benign and malignant) has been reported in patients that survived their cancer and were treated with somatropin. Of these second tumours, in particular, brain tumours were the most common.
If you have symptoms such as frequent or bad headache, with nausea and/or vision problems occur, tell your doctor immediately. Your doctor should perform an examination of the eyes to look for evidence of increased brain pressure. Depending on the results of this examination, treatment with Humatrope may have to be interrupted.
If you develop a limp or pain in the hip, please ask your doctor for advice. During periods of growth, you may develop bone disorders in your hips.
If you start treatment, Humatrope can affect the amount of thyroid hormones in your blood. If the thyroid hormone level is low, it may reduce your response to Humatrope. Therefore, you must have regular thyroid function tests regardless whether you receive thyroid hormone therapy or not.
If you are a child, make sure that you continue treatment until the end of growth has been reached.
If you take a higher than prescribed dose of Humatrope, you may experience overgrowth of some parts of your body such as ears, nose, jaw, hands and feet. Overdose may also lead to increased levels of blood sugar and sugar in the urine. Always use Humatrope as recommended by your doctor.
If you have growth disorder due to kidney damage, treatment with Humatrope should be stopped prior to kidney transplantation.
If you have acute critical illness, your treating doctor should be notified. Deaths have been reported in patients receiving somatropin during critical illness.
If you are growth hormone deficient and also have Prader-Willi syndrome (a genetic disorder), your doctor should examine you for breathing problems and airway infections before starting Humatrope treatment, especially if you are overweight, have previously experienced severe breathing problems (especially during sleep), or suffered infection of the lungs or airways. If during treatment you have signs of breathing problems (snoring), treatment should be interrupted and the cause assessed by your
Humatrope may affect the way your body handles sugar from food and drink by interfering with the way your body uses insulin. Therefore, if you take Humatrope, your doctor should check if your body is dealing with the sugars correctly.
If you have diabetes mellitus, your insulin dose may need to be adjusted after starting Humatrope treatment. Your doctor will check the amount of sugar in your blood and may adjust your diabetes therapy.
If you have a growth disorder associated with being born small for gestational age, your blood sugar and insulin levels will be checked before starting the treatment and regularly during treatment.
Elderly patients (over 65 years) may be more sensitive to Humatrope and may be prone to side effects.
Children who are treated with somatropin have an increased risk of developing an inflammation of the pancreas (pancreatitis) compared to adults treated with somatropin. Although rare, pancreatitis should be considered in somatropin-treated children who develop abdominal pain.
Scoliosis (an increase in sideways curvature of the spine) may progress in any child during rapid growth. Signs of scoliosis should be monitored during treatment
Other medicines and Humatrope
Tell your doctor or pharmacist if you are using, have recently used or are planning to use any other medicines.
In particular, inform your doctor if you are taking or have recently taken any of the following medicines. Your doctor may need to adjust the dose of Humatrope or of the other medicines:
- medicines for the treatment of diabetes mellitus which may have to be adjusted.
- adrenal steroid hormone (glucocorticoid), such as cortisone or prednisolone; your doctor may need to adjust the dose because the combination of these medicines with Humatrope may reduce the effect of both treatments.
- Oestrogen taken orally or other sex hormones, as it may affect the response to growth hormone treatment. If there is a change to the way oestrogen is taken (e.g. oral to transdermal: through the skin); Humatrope dose may need to be adjusted.
- medicines to prevent seizure (anticonvulsants) or cyclosporine.
Pregnancy and breast feeding
Humatrope should not be used during pregnancy, unless your doctor tells you to do so. If you become pregnant, tell your doctor immediately.
It is not known whether somatropin enters the breast milk. If you are breast-feeding, or intend to breast-feed, please ask your doctor for advice before using Humatrope.
Driving and using machines
Humatrope has no known effect on ability to drive or use machines.
Humatrope contains sodium
This medicine contains less than 1 mmol sodium (23mg) per daily dose, that is to say essentially sodium- free.